VDRL (RPR) Quantitative Test

The VDRL (Venereal Disease Research Laboratory) test, also known as RPR (Rapid Plasma Reagin) when performed as a quantitative test, is a non-treponemal serological test used primarily for screening and monitoring syphilis infections. Here's some key information about this test:

Purpose of VDRL Quantitative Test?

• • Screening for syphilis
  • Monitoring the progression of syphilis infection
  • Evaluating the effectiveness of syphilis treatment

What VDRL Quantitative Test measures?

• • The test detects antibodies produced in response to lipid molecules released from damaged host cells during syphilis infection.
  • It's not specific to Treponema pallidum (the bacterium that causes syphilis), which is why it's called a non-treponemal test.

Quantitative aspect;

• • The quantitative version of the test provides a titer, which indicates the amount of antibody present.
  • Titers are typically reported as dilutions (e.g., 1:8, 1:16, 1:32).

Interpretation of VDRL Quantitative Test

• • A positive result suggests the possibility of syphilis but requires confirmation with a treponemal-specific test.
  • Titer levels can help monitor disease progression and treatment effectiveness.
  • Falling titers generally indicate successful treatment.
  • Rising titers may suggest reinfection or treatment failure.

Limitations of VDRL Quantitative Test

• • Can produce false-positive results due to other conditions (e.g., autoimmune diseases, pregnancy, viral infections)
  • May be negative in very early or late stages of syphilis

Use in treatment monitoring;

• • Quantitative results are particularly useful for monitoring treatment response.
  • A four-fold decrease in titer (e.g., from 1:32 to 1:8) usually indicates successful treatment.

It's important to note that while this test is valuable, it should be interpreted in conjunction with clinical findings and other syphilis-specific tests for accurate diagnosis and management.

Detect the presence and measure the amount of VDRL (RPR) in your body with this quantitative test, now available at an affordable price of ₹499. Stay informed about your health and receive accurate results quickly.