Total IgE Test
Serum Total IgE Test
Serum total IgE test determines levels of allergen-specific immunoglobulin E (IgE) in the blood to help diagnose an allergy to a particular substance.
Note: Read test details, FAQs and test conditions before proceeding to booking.
Total IgE Test
Serum IgE Level Test
Immunoglobulins E Immunoassay Blood test helps to check whether an individual is having normal or abnormal levels of IgE in the blood.
What is the total IgE test?
Total IgE Test – Allergies are an extensive, widespread condition in our society. So much so that 40% of children and 30% of adults in the US are vulnerable to allergies.
The long list of types of allergies people face is indeed exhaustive. For instance, few have an allergy to drugs (medicines). Even though the number is very few, the allergy is mainly caused because of the side effects the medicine can have on an individual, which highly depends on one person to another.
The most common of all we see is the intolerance people have towards particular food items such as dairy, eggs, peanuts, shellfish, and even milk, which is extensive in children.
Insects such as wasps, bees, and hornets can be troublesome for a few in over one way. One allergy that can pose a severe health risk is the allergy to latex. Latex is the milky fluid that is observed in trees and plants when they are cut and exposed to air.
Latex, from the rubber tree, also is a vital source of natural rubber. Individuals who are allergic to latex will distance themselves from gloves and balloons.
Other kinds of allergies, which are well known, include an allergy to pets. The allergy is predominantly because of the fur. Pollen allergies are seasonal but very common.
More commonly known as hay-fever, from an expert point of view, they are known as seasonal allergic rhinitis. Mold allergy is another type that involves being allergic to fungi and mildew.
So, it is quite clear from the aforementioned paragraphs that we all don’t share the same allergy, or even, fortunately, we might not even be allergic to any of these. But, it can clearly be understood that an allergy, as a strong dislike for something, could purely depend on an individual.
What you are allergic to is perceived as a foreign invader by your immune system, which is the reason it reacts differently.
An allergy, crudely, could be simply described as an overreaction by our immune system. The antibody named Immunoglobulin E, which is more commonly know as IgE, is produced by the immune system for allergens, and these antibodies travel to the cells to instigate them to release a chemical which will cause an allergic reaction.
IgE is a protein associated with allergic reactions. It is normally found in minimal amounts in the blood. IgE is produced by plasma cells. It is an antibody that functions as part of the body’s immune system. It is released by the immune system to fight against the foreign bodies and allergens that enter the body. IgE antibodies are found in the skin, lungs, and mucous membranes of the body.
They cause reactions as soon as they detect any environmental allergen, such as pollen, fungus, spores, or dander. The body perceives the potential allergen as a foreign substance and produces a specific IgE antibody that binds to specialized mast cells in the skin, respiratory system, and gastrointestinal tract, and to basophils in the bloodstream.
During the next exposure, the attached IgE antibodies recognize the allergen and cause the mast and basophil cells to release histamine and other chemicals, resulting in an allergic reaction. People with allergies often have elevated IgE levels. IgE plays an important role in conditions such as asthma and various allergies, atopic dermatitis, certain types of cancer, and is mostly associated with type 1 hypersensitivity. IgE levels are also elevated in children with parasitic infections.
Why total IgE test is advised?
The doctor may ask you to undergo this test if you are suffering from symptoms such as delayed walking, skin discoloration, decreased mental development, pain in bones, loss of appetite, constipation, etc. This test is also done if an individual is suffering from recurrent infections, such as skin infections, kidney damage, respiratory infections, parasite infections, etc.
If an individual is on the treatment for the immunodeficiency Immune system to fight against infections is absent or not working, then the doctor may ask to perform this test to evaluate and to check the effectiveness of the treatment.
How often serum total IgE test should do?
If you have been diagnosed with immunodeficiency, your doctor may advise you to get this test done once in a year based on your clinical condition. If you are a healthy individual above the age of 35, your doctor may advise you to undergo this test either yearly or every other year.
When do IgE level blood test?
Allergies show the alarming level of IgE in our blood. Even though allergies are most commonly not fatal, they can easily have a substantial effect on us. They can have grim implications if the IgE level in the blood is not taken care of accordingly and in the prescribed period.
- Hives: These are itchy and often lumpy rashes that can be observed on the person’s skin. Urticaria is the medical term and these rashes can easily spread over someone’s body. Overly exposed to the sun, food intake which is intolerant to the system are some causes for hives. Hives are one of the sure-shot ways of indicating elevated levels of IgE in the blood.
- Sneezing; To sneeze once in a while is easily distinguishable from the sneezes that are erratic, uncontrollable, and result in watery eyes and stuffy, runny nose. The duration and the frequency of this problem arises are the indications of inappropriate levels of IgE in the system.
- Nasal congestion: Also known as stuffy nose, nasal obstruction, and nasal blockage, this condition can be observed when the membranes lining the nose swell because of inflamed blood vessels. The blood vessels inflame because of a biological response to pathogens, damaged cells, or irritants.
- Tight throat: This also goes by the name swollen throat, which is usually caused because of increased levels of histamine, IgE levels, and other chemicals throughout the body.
- Trouble breathing: People suffering from hyper-IgE syndrome usually suffer from recurring bacterial pneumonia. More commonly observed in children, patients with high IgE have a higher possibility of having lung tissue damaged, and it can also result in chronic lung disease.
- Dermatitis: This medical condition in which the skin can become red, swollen and itchy usually signifies an upsetting level of IgE in the blood. Sometimes people who are prone to dermatitis will also be vulnerable to food allergy, asthma, and allergic rhinitis.
- Eczema: Recent research does point out that eczema, which is more commonly observed in children, may not be because of an allergy. But what it points out is that abnormal functioning of the immune system and genetics play a crucial role. Hence, this condition must not be overlooked.
- Abdominal pain: The frequency and the duration for which this usually occurs in children shows a higher level of IgE in blood.
- Vomiting and diarrhea: Similar to dermatitis, patients who suffer from hyper IgE, along with suffering from vomiting and diarrhea, are intolerant to certain food and show other common hyper IgE symptoms.
Other symptoms include:
- Red itchy eyes
- Itching and tingling in the mouth
Symptoms may be seasonal (as with allergies because of pollen or moulds) or year-round (as with food allergies).
Total IgE test conditions
IgE serum test determines levels of allergen-specific immunoglobulin E (IgE) in the blood to help diagnose an allergy to a particular substance. IgE is one of the five classes of antibodies. Antibodies are proteins created by the immune system that attack antigens, such as bacteria, viruses, and allergens, and neutralize the foreign objects that find entry into the body.
IgE antibodies are found in the lungs, skin, and mucous membranes. They are associated mainly with allergic reactions (when the immune system overreacts to environmental antigens such as pollen or pet dander) and parasitic infection.
- Overnight fasting is not required
- Doctor’s prescription may be needed
- The normal reference range may vary depending on gender, age, health history, etc.
- Also advised for allergy detection
- Home visit collection facility for IgE test available in Pune and PCMC for total test amount above Rs999.00
Also known as, Serum IgE Test, Serum IgE Total, Total IgE Immunoassay Blood, Immunoglobulin E, Serum IgE, Total IgE,
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