HLA-B*5701 Test

HLA-B5701 testing is a genetic test that detects the presence of the HLA-B5701 allele, a genetic variant that is associated with an increased risk of hypersensitivity reactions to abacavir, a medication used to treat HIV. The HLA-B*5701 allele is found in approximately 6% of the population and is more commonly found in certain ethnic groups, such as Caucasians and people of Ashkenazi Jewish descent.

At healthcare nt sickcare, an ISO 9001:2015 certified online medical laboratory, we offer HLA-B*5701 testing as part of our comprehensive range of clinical laboratory testing and reporting services. Our team of experienced and highly skilled medical professionals uses state-of-the-art equipment and technology to ensure the accuracy and precision of every test result.

HLA-B5701 testing involves a simple blood test, which is analysed to detect the presence or absence of the HLA-B5701 allele. A positive result for the HLA-B*5701 allele indicates an increased risk of hypersensitivity reactions to abacavir, while a negative result indicates a lower risk.

Hypersensitivity reactions to abacavir can be serious and potentially life-threatening, and can occur in up to 8% of patients treated with abacavir who have the HLA-B*5701 allele. Symptoms of hypersensitivity reactions to abacavir can include fever, rash, fatigue, nausea, vomiting, diarrhoea, and abdominal pain. In severe cases, hypersensitivity reactions to abacavir can lead to respiratory failure, liver failure, and death.

HLA-B5701 testing can help healthcare providers determine if a patient is at increased risk of hypersensitivity reactions to abacavir, and can guide treatment decisions for HIV patients. Patients who test positive for the HLA-B5701 allele can be prescribed alternative medications to avoid the risk of hypersensitivity reactions to abacavir.

At healthcare nt sickcare, we understand the importance of timely and accurate diagnosis. That's why we offer HLA-B*5701 testing as part of our commitment to providing empowered patient care. Our E-commerce website, healthcarentsickcare.com, makes it easy for patients to book lab tests online and receive their test results in a timely and convenient manner.

Why is the HLA-B5701 test important?

This test determines if a patient carries a gene variant that increases hypersensitivity risk to abacavir, an HIV medication. This allows safer treatment decisions.

What is tested?

The test detects the presence of the HLA-B5701 allele. This genetic marker is found in around 6% of people and increases abacavir allergy risk.

What do results mean?

A positive result means a person has higher risk of abacavir hypersensitivity. A negative result signals lower risk. This guides HIV treatment choices.

If you are HIV-positive or at risk of HIV and are considering treatment with abacavir, HLA-B5701 testing can help determine if you are at increased risk of hypersensitivity reactions to abacavir. Contact healthcare nt sickcare today to learn more about HLA-B5701 testing and our other clinical laboratory testing and reporting services.