IMMUNOGLOBULIN E (IGE) DEFINITION
Immunoglobulin E (IgE) are antibodies produced by the immune system.
If you have an allergy, your immune system overreacts to an allergen by producing antibodies called Immunoglobulin E (IgE). These antibodies travel to cells that release chemicals, causing an allergic reaction. This reaction usually causes symptoms in the nose, lungs, throat, or on the skin.
Each type of IgE has specific “radar” for each type of allergen. That’s why some people are only allergic to cat dander (they only have the IgE antibodies specific to cat dander); while others have allergic reactions to multiple allergens because they have many more types of IgE antibodies.
IgE & Allergy
Allergies are a common and chronic condition that involves the body’s immune system. Normally, your immune system works to fight off viruses, bacteria, and other infectious agents. When you have an allergy, your immune system treats a harmless substance, like dust or pollen, as a threat. To fight this perceived threat, your immune system makes antibodies called immunoglobulin E (IgE).
Substances that cause an allergic reaction are called allergens. Besides dust and pollen, other common allergens include animal dander, foods, including nuts and shellfish, and certain medicines, such as penicillin. Allergy symptoms can range from sneezing and a stuffy nose to a life-threatening complication called anaphylactic shock. Allergy blood tests measure the amount of IgE antibodies in the blood. A small amount of IgE antibodies is normal. A larger amount of IgE may mean you have an allergy.
Other common names of IgE: IgE allergy test, Quantitative IgE, Immunoglobulin E, Total IgE, Specific IgE
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What is IgE Allergy Test?
Allergy blood tests are used to find out if you have an allergy. One type of test called a total IgE test measures the overall number of IgE antibodies in your blood. Another type of allergy blood test called a specific IgE test measures the level of IgE antibodies in response to individual allergens.
A number of different allergens are responsible for allergic reactions. The most common include:
• Insect stings
• Animal dander
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