Anti CCP Antibody Test
Anti CCP Antibodies Test – Anti Cyclic Citrullinated Peptide Antibodies test is performed on a sample of blood to measure the level of Anti CCP Antibodies in the blood. It is performed to confirm Rheumatoid Arthritis and also during the treatment and after the treatment of Rheumatoid Arthritis.
What is CCP?
CCP meaning is Cyclic citrullinated peptide, it is a circular peptide that contains the amino acid citrulline. Both citrullination and anti-citrullinated peptide antibodies play an important role in initiating inflammatory responses in autoimmune diseases like a rheumatoid disease.
What is Anti-CCP?
The Anti- CCP Test is a blood test that can be used by doctors to confirm a diagnosis of rheumatoid arthritis. The ACCP test detects the presence of citrulline antibodies in the blood.
A positive Anti- Ccp Test result could be used in conjunction with other blood tests, physical examinations, and imaging tests to confirm rheumatoid arthritis diagnosis. The anti – CCP test normal range is less than 20 u/ml. A level above 20 is indicative of the possibility of Rheumatoid Arthritis.
These anti -CCP’s are proteins produced by the immune system in response to the perceived threat from citrulline. The Anti – Ccp is directed by the body against the peptides and proteins that are citrullinated. These autoantibodies are found to be present in a large majority of people affected by Rheumatoid arthritis.
RA is a chronic systemic autoimmune disease that causes inflammation, pain, stiffness, and destructive changes in the hands, feet, and other joints throughout the body. Conversion of arginine to citrulline plays a role in the autoimmune inflammatory process seen in the joints of those with Rheumatoid arthritis (RA).
Why Anti CCP Test Advised?
An anti-CCP test can be taken by any individual who may be susceptible to rheumatoid arthritis. General symptoms that may be observed are stiff joints that lead to painful walking or even holding of any objects by hand, especially in the morning or even after the body has rested for a while. Pain in the joints and bones, fatigue and low-grade fever.
- Anti-CCP Test For Rheumatoid Arthritis
- Advised along with RA Factor Test – Anti CCP is useful in diagnosing Rheumatoid arthritis and entities that may potentially be confused with Rheumatoid arthritis that is rheumatoid factor positive
Anti CCP Antibodies Test
- Overnight fasting is not required
- Doctor’s prescription may be needed
- The normal test result may vary depending on gender, age, health history, etc.
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