Stool Calprotectin Test

Description

Stool Calprotectin Test

Calprotectin is a stool (fecal) test that is used to detect inflammation in the intestines and digestive system. Intestinal inflammation is associated with bacterial infections and in people with inflammatory bowel disease (IBD). Signs and symptoms of IBD will vary from person to person and. They may include;

• Bloody or watery diarrhea
• Abdominal cramps or pain
• Fever
• Weight loss
• Rectal bleeding
• Weakness

Why tool calprotectin test advised?

Stool test for calprotectin is prescribed by doctors when they suspect irritable bowel syndrome in their patients. Calprotectin tests are useful in distinguishing between IBD and non-inflammatory bowel condition. Determination of the levels of fecal calprotectin is also useful in pediatrics and neonatology. High sensitivity and specificity of calprotectin makes it more reliable for detecting bowel information in infants and newborns.

Stool sample for the calprotectin test

There is no specific test preparation that is to be taken before the collection of the sample. The stool sample is collected in a clean container provided either by the laboratory or you can buy it from medical stores. This sample should be uncontaminated by urine or water. The sample should be taken to our laboratory for testing and it may take a few days before results are available.

Stool calprotectin test result

The stool sample taken is tested for calprotectin levels. Calprotectin is released by neutrophils, which is a type of white blood cell. When there is inflammation in the gastrointestinal (GI) tract, neutrophils move to the area and release calprotectin which results in an increased level of the protein in the stool. This test measures the calprotectin levels in the stool to detect inflammation in the intestines.

The results of a calprotectin test are given as a single number. This number will be compared against the cut-off value for the calprotectin test. If the number is below the cut-off value, it is considered being at normal levels. If the levels are above the cut-off value, it is positive and abnormal. The fecal calprotectin test may be repeated if the level is near the cutoff value at a later date.

Calprotectin Stool Test

Calprotectin Stool Test Limitations: False-negative results could occur in patients who have granulocytopenia due to bone marrow depression.

Note:

• Overnight fasting, not required
• Doctor’s prescription may be required
• Previous medical report and test history may be needed
• The normal reference range may vary depending on age, health history, etc.
• False-negative results could occur in patients who have granulocytopenia due to bone marrow depression.
• No Home Visit Collection Facility For Calprotectin Test. Drop the sample at the lab during working hours.

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