ANA by IFA Blood Test
ANA by IFA Test – The antinuclear IMMUNOFLUORESCENCE panel is a blood test that appears at antinuclear antibodies (ANA). Antinuclear antibodies are substances produced by the immune system that attack the body’s own tissues.
What is ANA by IFA?
ANA refers to Antinuclear antibodies. These are antibodies produced by the immune system of the body against protein markers found in the nucleus of its own cells. The Antinuclear Antibody Test measures the amount and pattern of antinuclear antibodies in the blood.
Why is ANA by IFA Test Done?
- To determine the presence of an autoimmune disease like Systemic Lupus Erythematosus (SLE)
- To evaluate the possible presence of autoimmune Connective Tissue Disorders (CTDs) other than SLE such as Polymyositis, Scleroderma, Sjögren’s syndrome, etc.
What does ANA by IFA Blood Test Measure?
The Antinuclear Antibody (ANA) test measures the amount and pattern of antinuclear antibodies in the blood. The immune system of the body is responsible for differentiating between the body’s own cells and foreign cells, like pathogens. Once the foreign cells are identified, they are then targeted and destroyed. In autoimmune disorders, the immune system of the body is unable to recognize certain cells as the body’s own cells and starts an immune response against them which results in their destruction.
The recognition of ‘self’ and ‘non-self’ cells is mediated by certain proteins present on the surface of cells or inside them. When the immune system identifies a cell as foreign or ‘non-self’, it produces antibodies against these cells to destroy them. Antibodies produced in an autoimmune disease are called autoantibodies.
Antinuclear antibodies (ANA) are autoantibodies that are produced against protein markers present in the nucleus of certain cells of the body. They are produced in a number of autoimmune diseases but are most commonly produced in Systemic Lupus Erythematosus (SLE).
The Antinuclear Antibody Test can be performed either by the Immunoassay method or Indirect Fluorescent Antibody (IFA) method to detect ANA in blood. Both these tests may be used by some laboratories together: the Immunoassay method screens for the presence of antinuclear antibodies, and the IFA method subsequently confirms the positive or equivocal Immunoassay results.
ANA by IFA Test
- Overnight fasting is not required
- Doctor’s prescription may be needed
- The normal test result may vary depending on gender, age, health history, etc.
- Home visit collection facility available for test amount above ₹499
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