Blood Flow and Veins

Why D Dimer Test is Done?

A blood test called D dimer test helps doctors diagnose deep vein thrombosis (DVT). The D–dimer normal range is less than or equal to 500 ng/mL.

What is the D Dimer Test?

A D-dimer test looks for D dimer in blood. D dimer is a protein fragment (small piece) that’s made when a blood clot dissolves in your body.

Blood clotting is an important process that prevents you from losing too much blood when you are injured. Normally, your body will dissolve the clot once your injury has healed. With a blood clotting disorder, clots can form when you don’t have an obvious injury or don’t dissolve when they should. These conditions can be very serious and even life-threatening. A D-dimer test can show if you have one of these conditions.

Why D Dimer Test Advised?

A D-dimer test is most often used to find out whether you have a blood clotting disorder. These disorders include:

  • Deep vein thrombosis (DVT), a blood clot that’s deep inside a vein. These clots usually affect the lower legs, but they can also happen in other parts of the body.
  • Pulmonary embolism (PE), a blockage in an artery in the lungs. It usually happens when a blood clot in another part of the body breaks loose and travels to the lungs. DVT clots are a common cause of PE.
  • Disseminated intravascular coagulation (DIC), a condition that causes too many blood clots to form. They can form throughout the body, causing organ damage and other serious complications. DIC may be caused by traumatic injuries or certain types of infections or cancer.
  • Stroke a blockage in the blood supply to the brain.

What is the D Dimer Test Method?

There are currently four major types of commercial assays that can measure D-dimer levels, which include whole blood analysis enzyme-linked immunosorbent assay (ELISA), enzyme-linked immunofluorescence assay (ELFA) and Latex-enhanced immuno-turbidimetric assay.

Several studies have found the ELFA method to provide the highest sensitivity for detecting D-dimer levels; however, the specificity of this method is approximately 46%. Similar sensitivity to D-dimer levels of 94% and 93% are being reported with the ELISA and Latex methods, respectively; however, these methods are also limited in their specificity capabilities that both average at 53%.

Although the sensitivity of these assays is valuable, they are limited where there is a high probability that the patient has DVT, PE, or is experiencing some other type of serious thrombotic event. In these situations, clinicians will often order compression ultrasonography and computed tomography pulmonary angiography to confirm DVT or PE diagnoses, respectively.

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What is d dimer test in covid 19?

It is estimated that 10-15% of COVID-19 patients will experience critical forms of this disease that progress to severe pneumonia, hypoxia, and respiratory failure, all of which will require supportive care and supplemental nasal oxygen.

About 5% of these severe COVID-19 cases have been found to decline even further to acute respiratory distress syndrome (ARDS) or multiple organ failure (MOF), both of which require intensive care unit (ICU) admittance with mechanical ventilation or extracorporeal membrane oxygenation (ECMO). 

Despite the widespread cases and severe forms of COVID-19 that have been reported, there remains a limited understanding of why certain individuals develop ARDS and MOF and others do not.

To improve the early identification of these severe forms of COVID-19, many researchers have committed themselves and their teams to identify reliable biomarkers.

What is the d dimer test normal range?

The D–dimer normal range is less than or equal to 500 ng/mL

D dimer test normal range – The reference range/cutoff value for D dimer is ideally established by the performing laboratory, or, if a cutoff value published in the literature is used, the value has to be determined with the same method, preferably from the same manufacturer.

  • If the D dimer test results come positive, then it means that the individual has blood clots in the body and higher than normal D dimer levels show to a significant amount of blood clot. 
  • A positive D dimer test results, however, do not point out the location of the blood clot and other screening tests might be required. 
  • If D dimer test results come negative, then it means there is no blood clots in the body. 
  1. Why Do I Need a D-Dimer Test?

    The reference range/cutoff value for D-dimer is ideally established by the performing laboratory, or, if a cutoff value published in the literature is used, the value has to be determined with the same method, preferably from the same manufacturer.
    The D–dimer test is given by a healthcare provider if he/she suspects the individual of having blood clotting problems, like Deep Vein Thrombosis, Pulmonary Embolism, Disseminated intravascular coagulation. The symptoms of blood clot are as follows; Leg swelling, leg pain, leg redness. The symptoms of blood clot in the lungs are as follows; Trouble breathing, coughing with blood, coughing, sweating,fainting, rapid heartbeat, chest pain.

  2. Any Preparations Required For D-Dimer Test?

    No special requirement is needed for the test and the blood sample is drawn out with the help of an injection. 

  3. Where can I Do D-Dimer Test in Pune?

    We offer D dimer lab tests at home as part of our expansive and highly trusted at–home healthcare services, wherein you can avail yourself a host of healthcare services ranging from doctor prescribed blood tests and preventative health checkup packages with a bunch of lab tests.
    Our healthcare service is like a walking clinic that visits your home, so you don’t have to spend your precious time travelling and waiting for your turn and rather spend it relaxing or with family. healthcare nt sickcare laboratory’s D dimer lab tests are conducted by a highly trained technician and the blood sample for the lab test is collected from the patient’s home itself and the D-dimer test results are also made available online.

  4. What Is D Dimer Test Measured?

    The presence of D-dimer in the blood plasma, which has a half-life of roughly 8 hours until kidney clearance occurs, is often used as a clinical biomarker to identify thrombotic activity and therefore diagnose conditions like pulmonary embolism (PE), deep vein thrombosis (DVT), venous thromboembolism (VTE) and disseminated intravascular coagulation (DIC).
    Some of the risk factors for conditions like VTE that will support a clinician’s interest in quantifying D-dimer levels include active cancer, immobilization, or recent surgery. Other conditions that can cause D-dimer levels to rise include advanced age, pregnancy, and chronic inflammatory diseases.

  5. What is D Dimer?

    D-dimer is a fibrin degradation product that is often used to measure and assess clot formation. Amid the COVID-19 pandemic, elevated D-dimer levels have been associated with disease severity and mortality trends.

  6. How Much D Dimer Test Cost Me?

    healthcare nt sickcare charge Rs1499.00 for d dimer blood test, including home visit collection facility in Pune and Pimpri Chinchwad.

  7. Any Side Effect After D Dimer Test?

    The D dimer test is safe to use and side effects are a rarity. The varied side effect of the test may include; Soreness at the puncture site, excessive bleeding, dizziness, infections at the puncture site.

You May Also Interest To Read; How to Protect From Coronavirus?

Reference: News Medical And MedilinePlus

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