Pathology Laboratory

What is the C Peptide Test?

Last updated on October 20th, 2022 at 09:12 am

A C peptide test is a tool your doctor uses to monitor and treat diabetes. It shows how well your body makes insulin, which moves sugar (or “glucose”) from your blood into your cells.

What is the C peptide test?

C Peptide test can help your doctor decide whether you need to take insulin to control your condition or to check your dosage if you already take it.

Doctors can use the test whether you have type 1 diabetes when the immune system attacks and destroys cells in the pancreas, or type 2, when your body doesn’t use insulin as well it should.

Beta cells in your pancreas make insulin. During that process, these cells also release C-peptide.

This substance doesn’t actually affect your blood sugar. But your doctor can mean C-peptide and C-peptide test level of it to help to figure out how much insulin you’re making.

C-Peptide and diabetes

Doctors don’t use it to diagnose diabetes, but it can give them a reading to help treat it.

It can tell the difference between insulin your body has made and the insulin that you took.

You might get the C-peptide test:

  • To find out whether you have type 1 or type 2 diabetes
  • When you have type 1 and your doctor needs to know how much insulin your pancreas still makes
  • When you have type 2 diabetes and she needs to measure how much insulin you make on your own or whether you need to take it yet
  • To find out why you have low blood sugar (hypoglycemia)
  • To diagnose a tumor of the pancreas that releases insulin, called an insulinoma
  • If you’ve had, your pancreas removed
How to prepare for the C-peptide test?

You might need to stop eating 10 to 12 hours before the test. Sometimes, it’s done after you eat.

Let your doctor know about any medicines you are on. Include medicine you take by prescription and those you buy over the counter, such as herbal supplements or vitamins.

C-Peptide measurement

The C-peptide test uses a sample of your blood and the result will be available in 24hrs.

C Peptide test normal range

A normal C-peptide range is 0.5 to 2.0 nanograms per millilitre.

These levels can be high when your body makes more insulin than usual. Levels are low when your body makes less than it normally should.

A high level can mean that you:

  • Have insulin resistance — meaning your body doesn’t use it as well as it should
  • Have a tumour, called an insulinoma
  • Have kidney disease

You may also be interested in reading: D-Dimer Test

High C-Peptide level in the blood

High levels of c-peptide with a low level of blood glucose could show insulin resistance, either type 2 diabetes or Cushing’s syndrome.

High levels of c-peptide but low blood glucose levels may result from insulinoma (a tumour of the pancreas) unless glucose-lowering medication has influenced the result.

Low C peptide level In the blood

Low levels of c-peptide and high blood glucose levels could be an indicator of type 1 diabetes.

Low levels of both c-peptide and blood glucose could show liver disease, a severe infection or Addison’s disease.

C Peptide Test in Pune

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