tTG IgG Test

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tTG IgG antibody test

Tissue Transglutaminase Antibody IgG test

tTG IgG test is primarily used to help diagnose and monitor celiac disease in people with signs and symptoms, including anaemia and abdominal pain.

Note: Read test details, FAQs and test conditions before proceeding to booking.


(For Home Visit Service, Minimum Total Test(s) Charges Should be ₹999)
(Confirm Slot Availability Before Choosing Time)

1) Home Collection Facility Available Only For Minimum Total Test(s) Charges Of ₹999.00 and above.
2) We Serve Only in Pune and Pimpri Chinchwad City Limits.
3) Additional Charges For Serving Outside Pune and Pimpri Chinchwad City Limits. (With in Pune)
4) Home Collection Facility Service Timing Should Be Selected Between 7.30am till 11.00am.
5) Direct Walk-in Service Timing Should Be Selected From 9.00am till 6pm (Monday-Saturday). Sunday from 9.00am till 1.30pm.
6) Confirm The Time Slot Availability Before Booking. There is No Auto Slot Blocking In Online Test Booking. You Should Reach to Use Over WhatsApp Or Call For Slot Availability.
7) We don't Provide Home Collection Service Only For Urine or Stool Test. These Tests Can Be Combined With Other Blood Tests.
8) Booking Date And Time Should Be 24hrs-72hrs in Advance

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tTG IgG Test

Tissue Transglutaminase Antibody – IgG test

Why tTG IgG tested?

To help diagnose celiac disease and to evaluate the effectiveness of a gluten-free diet.

When to get tTG IgG tested?

If you have symptoms such as chronic diarrhoea, bloating, abdominal pain, anaemia, and weight loss, it’s possible you have celiac disease. An infant can’t grow at a normal rate if they are chronically irritable. When a close family member has celiac disease; when you are being treated for celiac disease.

Any preparation needed for the tTG IgG test?

Follow your doctor’s instructions. For diagnosis, continue to eat foods that contain gluten for some time, such as several weeks, before testing. For monitoring celiac disease when you have already been diagnosed, no preparation is necessary.

Why tTG IgG test advised?

Celiac disease is an autoimmune disorder characterized by an inappropriate immune response to gluten, a protein found in wheat, and related dietary proteins in rye and barley. Celiac disease antibody tests help diagnose and monitor the disease and a few other gluten-sensitive conditions. These tests detect autoantibodies in the blood that the body produces as part of the immune response.

This immune response leads to inflammation of the small intestine and to damage and destruction of the villi that line the intestinal wall. The villi are projections, small tissue folds that increase the surface area of the intestine and allow nutrients, vitamins, minerals, fluids, and electrolytes to be absorbed into the body.

When a susceptible person is exposed to gluten, the person’s body produces autoantibodies that act against constituents of the intestinal villi. When villi are damaged or destroyed, the body is much less capable of absorbing food and develops signs and symptoms associated with malnutrition and malabsorption.

A tissue biopsy of the small intestine is still considered the gold standard to used to confirm a diagnosis of celiac disease, but the availability of less invasive blood tests to screen for celiac disease has reduced the number of biopsies needed.

Celiac disease blood tests measure the number of particular antibodies in the blood. The most common tests include:

  • Tissue transglutaminase antibody (tTG), IgA class the primary test ordered to screen for celiac disease. It is the most sensitive and specific blood test for celiac disease and is the single test preferred by doctors for the detection of celiac disease in those over the age of 2 years. If the test is positive, it can also monitor the condition and to help evaluate the effectiveness of treatment. (Although “tissue” is in the name of this test, it is measured in the blood.)
  • Immunoglobulin A (IgA) — this test is usually ordered along with the tTG IgA test (below) to detect IgA deficiency, which occurs in about 2-3% of people with celiac disease. If you have an IgA deficiency, then the test for tTG IgA may be negative even if you have celiac disease (false-negative test results). If the IgA test shows you have an IgA deficiency, then a test to detect the IgG class of autoantibodies may be advised.
  • tTG, IgG may be used as an alternative test in people who have a deficiency in IgA.
  • Deamidated gliadin peptide (DGP) antibodies (anti-DGP), IgA or IgG may be used in some people with suspected celiac disease who are negative for anti-tTG, especially children younger than 2 years old. DGP IgG testing along with anti-tTG IgG is recommended by doctors for people who have low IgA or IgA deficiency. If the anti-DGP test is positive, it may monitor celiac disease.

Celiac disease antibody tests are primarily used to help diagnose and monitor celiac disease in people with signs and symptoms, including anaemia and abdominal pain.

Sometimes celiac testing may screen for asymptomatic celiac disease in those who have close relatives with the disease since about 4-12% of them have or will develop celiac disease. Testing may also be advised in those who have other autoimmune diseases.

tTG IgG antibody test conditions


  • Overnight fasting is not required. Talk to your doctor before booking the test.
  • A doctor’s prescription may be required
  • A previous medical history may be required
  • Inform your doctor before the test and follow all of his/her advice. 
tTG IgG Blood Test

tTG IgG test also known as ttg igg test, ttg ab test, ttg igg levels, ttg igg blood test, anti ttg igg test, tissue transglutaminase test,

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Read Our Article On Celiac Disease

2 reviews for tTG IgG Test

  1. Vivek Nair

    ttg test is affordable in this lab

  2. 4 out of 5


    Appreciating your approach towards patient and family but the charges is high

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