Anti TPO Test

Description

Anti TPO Test

Anti TPO Test or thyroid peroxidase (TPO) is an enzyme of the thyroid gland. It is associated with the production of thyroid hormones. Anti TPO antibodies are produced against this enzyme. Such antibodies tear down the thyroid tissue and inflammation of the thyroid gland.

This is an autoimmune thyroid disorder, in which a person’s immune system attacks the thyroid gland and alters thyroid function. The test thus helps in diagnosing this disorder and distinguishing it from other forms of thyroid dysfunction.

Why anti TPO test advised?

A doctor prescribes the TPO test to detect and diagnose an autoimmune disorder of the thyroid gland. Anti TPO antibodies test is a common test for autoimmune thyroid disorders.

What are thyroid antibodies?

The immune system fights the bacteria and viruses attacking the body with substances called antibodies produced by blood cells called lymphocytes. Thyroid autoantibodies develop when the body mistakenly recognizes components of the thyroid as invaders and leads to inflammation of the thyroid, causing it to stop the production of thyroid hormone.

In hypothyroidism or hyperthyroidism, lymphocytes make antibodies against the thyroid, which damages or stimulates the gland, resulting in Graves’ disease and Hashimoto’s thyroiditis. Antithyroid peroxidase antibodies are significantly involved in thyroid dysfunction and the development of hypothyroidism.

Approximately 1% of the population suffers from thyroid disease, and as it presents itself with several symptoms, it needs to be diagnosed and constantly monitored to optimize treatment. Thyroid function tests are endocrine tests that detect the presence and measure the number of specific thyroid antibodies in the blood.

When is the anti TPO test referred?

A doctor refers to this test when other thyroid tests like TSH, Free T3, and T4 state thyroid dysfunction and when the thyroid gland is enlarged. The test may also be prescribed when the Anti TPO antibodies in the blood suggest Hashimoto’s disease or Grave’s disease.

Anti TPO Test

Note:

• Overnight fasting is not required
• Doctor’s prescription may be needed
• The test result may vary depending on gender, age, health history, etc.

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