24 Hour Urinary Protein Test

Description

24 hour Urinary Protein Test

What is a 24 hour urine protein test?

Proteins are the “building blocks” of the body. When the kidneys are healthy, no proteins pass into the urine. However, if the kidneys become diseased or damaged, the proteins may appear in the urine.

Hence, the urine protein test may screen for kidney disease, to monitor kidney function in those already diagnosed with kidney disease, or those who are taking medications that can affect the kidneys.

Why 24 hour urinary protein test advised?

A 24 hour urine protein measures the total amount of protein excreted in urine collected over 24 hours. Sometimes, to avoid the inconvenience and inaccuracy of a 24-hour urine collection, the protein-to-creatinine ratio may be done instead.

Protein-Creatinine Ratio (PCR) – The concentration of protein in the urine is compared to the creatinine level in a spot urine sample. It may monitor persistent proteinuria, i.e. presence of an excess of serum proteins in the urine. The protein in the urine often causes the urine to become foamy.

24 hour Urine Protein Test

Reasons for doctor referring 24-hour urine protein test;

Symptoms of a kidney-related disorder

• Poor appetite
• Fatigue
• Lack of concentration
• Trouble sleeping
• Swelling or puffiness, especially around the eyes or in the face, ankles, hands, feet
• abdomen wrists, abdomen and thighs
• Foamy, bloody, or dark-coloured Urine
• Reduced urine output or change in the frequency of urination
• Discomfort during urination (burning sensation)
• Mid-back pain
• Pain below the ribs (location of the kidneys)
• High blood pressure

How to collect a urine sample for a 24 hour urine protein test?

Specimen type: Urine Specimen collection procedure 24-hour urine sample.

Care must be taken to clean the genitals well before collection.

Follow these steps to get the sample

• Day 1- The first morning urine sample on Day 1 must not be collected, i.e. bladder must be emptied for the first time.
• Note down the exact time of discarding the 1st urine sample.
• All urine for the next 24 hours should be collected in the special container provided.
• Day 2- collect the first-morning urine of Day 2 into the same container, at the same time or within 10 minutes as that noted on the morning of Day 1.
• Cap the container. Keep it in the refrigerator or a cool place during the collection period.

24 hour Urinary Protein test Reference Range

Reference Range-Interpretation

10-140 mg/dL(24 hours)>Normal

24 Hour Urinary Protein Test

Note:

• Overnight fasting is not required. Talk to your doctor before booking the test.
• A doctor’s prescription may be required
• A previous medical history may be required
• Inform your doctor before the test and follow all of his/her advice
• Home visit collection facility is not available for 24 hour urine protein test

24 Hour Urine Protein Test

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Click to read our detailed article on Microalbuminuria